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Chemotherapy (doublet or triplet) plus targeted therapy by RAS status as conversion therapy in colorectal cancer patients with initially unresectable liver-only metastases. The UNICANCER PRODIGE-14 randomised clinical trial.
Ychou, Marc; Rivoire, Michel; Thezenas, Simon; Guimbaud, Rosine; Ghiringhelli, Francois; Mercier-Blas, Anne; Mineur, Laurent; Francois, Eric; Khemissa, Faiza; Chauvenet, Marion; Kianmanesh, Reza; Fonck, Marianne; Houyau, Philippe; Aparicio, Thomas; Galais, Marie-Pierre; Audemar, Franck; Assenat, Eric; Lopez-Crapez, Evelyne; Jouffroy, Claire; Adenis, Antoine; Adam, René; Bouché, Olivier.
  • Ychou M; Department of Digestive Oncology, Institut du Cancer de Montpellier, Montpellier, France. marc.ychou@icm.unicancer.fr.
  • Rivoire M; Department of Surgical Oncology, Léon Bérard Cancer Center, Lyon, France.
  • Thezenas S; Biometrics Unit, Institut du Cancer de Montpellier, Montpellier, France.
  • Guimbaud R; Department of Digestive Oncology - IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France.
  • Ghiringhelli F; Department of Medical Oncology, Centre Georges François Leclerc, Dijon, France.
  • Mercier-Blas A; Department of Medical Oncology, Centre Hospitalier Privé de Saint-Grégoire, Saint-Grégoire, France.
  • Mineur L; Department of Digestive Oncology, Institut Sainte Catherine, Avignon, France.
  • Francois E; Department of Medical Oncology, Centre Antoine Lacassagne, Nice, France.
  • Khemissa F; Gastroenterology unit, Centre Hospitalier Saint-Jean, Perpignan, France.
  • Chauvenet M; Department of Hepato-gastroenterology and Digestive Oncology, Hôpital Lyon Sud, Lyon, France.
  • Kianmanesh R; Department of Digestive and Endocrine Surgery, Hôpital Robert Debré, Reims, France.
  • Fonck M; Department of Digestive Oncology, Institut Bergonié, Bordeaux, France.
  • Houyau P; Department of Medical Oncology, Clinique Claude Bernard, Albi, France.
  • Aparicio T; Department of Gastroenterology and Digestive Oncology, Hôpital Saint Louis, APHP, Paris, France.
  • Galais MP; Department of Medical Oncology, Centre François Baclesse, Caen, France.
  • Audemar F; Gastroenterology unit, Centre hospitalier Côte Basque, Bayonne, France.
  • Assenat E; Department of Digestive Oncology, CHU Saint Eloi, Montpellier, France.
  • Lopez-Crapez E; Translational Research Unit, Institut du Cancer de Montpellier, Montpellier, France and IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier, Montpellier, France.
  • Jouffroy C; R&D Unicancer, Paris, France.
  • Adenis A; Department of Digestive Oncology, Institut du Cancer de Montpellier, Montpellier, France.
  • Adam R; Hepatobiliary Centre, Paul Brousse Hospital, AP-HP, Villejuif, France.
  • Bouché O; Department of Hepatogastroenterology and Digestive Oncology, Hôpital Robert Debré, Reims, France.
Br J Cancer ; 126(9): 1264-1270, 2022 05.
Article en En | MEDLINE | ID: mdl-34992255

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Neoplasias Colorrectales / Neoplasias Hepáticas Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans / Male / Middle aged Idioma: En Año: 2022 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Neoplasias Colorrectales / Neoplasias Hepáticas Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans / Male / Middle aged Idioma: En Año: 2022 Tipo del documento: Article