Metabolic Imaging Using Hyperpolarization for Assessment of Premalignancy.
Methods Mol Biol
; 2435: 169-180, 2022.
Article
en En
| MEDLINE
| ID: mdl-34993946
ABSTRACT
There is an unmet need for noninvasive surrogate markers that can help identify premalignant lesions across different tumor types. Here we describe the methodology and technical details of protocols employed for in vivo 13C pyruvate metabolic imaging experiments. The goal of the method described is to identify and understand metabolic changes, to enable detection of pancreatic premalignant lesions, as a proof of concept of the high sensitivity of this imaging modality.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Lesiones Precancerosas
/
Ácido Pirúvico
Tipo de estudio:
Screening_studies
Límite:
Humans
Idioma:
En
Año:
2022
Tipo del documento:
Article