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Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia.
Poli, Valentina; Di Gioia, Marco; Sola-Visner, Martha; Granucci, Francesca; Frelinger, Andrew L; Michelson, Alan D; Zanoni, Ivan.
  • Poli V; Harvard Medical School, Boston Children's Hospital, Division of Immunology, Boston, MA, USA.
  • Di Gioia M; Harvard Medical School, Boston Children's Hospital, Division of Immunology, Boston, MA, USA.
  • Sola-Visner M; Harvard Medical School, Boston Children's Hospital, Division of Newborn Medicine, Boston, MA, USA.
  • Granucci F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, INGM-National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi", Milan, Italy.
  • Frelinger AL; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
  • Michelson AD; Center for Platelet Research Studies, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
  • Zanoni I; Harvard Medical School, Boston Children's Hospital, Division of Immunology, Boston, MA, USA; Harvard Medical School, Boston Children's Hospital, Division of Gastroenterology, Boston, MA, USA. Electronic address: ivan.zanoni@childrens.harvard.edu.
Immunity ; 55(2): 224-236.e5, 2022 02 08.
Article en En | MEDLINE | ID: mdl-34995475
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plaquetas / Agregación Plaquetaria / Sepsis / Factores de Transcripción NFATC Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Plaquetas / Agregación Plaquetaria / Sepsis / Factores de Transcripción NFATC Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article