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Fingerprint sign in Vogt-Koyanagi-Harada disease: a case series.
Missaka, Ruy Felippe Brito Gonçalves; Goldbaum, Mauro; Machado, Cleide Guimarães; Cunningham, Emmett T; Souto, Fernanda Maria Silveira; Lavezzo, Marcelo Mendes; da Nóbrega, Priscilla Figueiredo Campos; Sakata, Viviane Mayumi; Oyamada, Maria Kiyoko; Hirata, Carlos Eduardo; Yamamoto, Joyce Hisae.
  • Missaka RFBG; Department of Ophthalmology, LIM-33, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, 01246-000, Brazil. ruymissaka@gmail.com.
  • Goldbaum M; Brazilian Vogt-Koyanagi-Harada Disease Study Group, São Paulo, SP, Brazil. ruymissaka@gmail.com.
  • Machado CG; Department of Ophthalmology, LIM-33, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, 01246-000, Brazil.
  • Cunningham ET; Department of Ophthalmology, LIM-33, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, 01246-000, Brazil.
  • Souto FMS; West Coast Medical Group, San Francisco, CA, USA.
  • Lavezzo MM; Department of Ophthalmology, California Pacifical Medical Center, San Francisco, CA, USA.
  • da Nóbrega PFC; Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA.
  • Sakata VM; The Francis I Proctor Foundation, UCSF School of Medicine, San Francisco, CA, USA.
  • Oyamada MK; Department of Ophthalmology, LIM-33, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, 01246-000, Brazil.
  • Hirata CE; Brazilian Vogt-Koyanagi-Harada Disease Study Group, São Paulo, SP, Brazil.
  • Yamamoto JH; Department of Ophthalmology, LIM-33, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, 01246-000, Brazil.
Int J Retina Vitreous ; 8(1): 7, 2022 Jan 10.
Article en En | MEDLINE | ID: mdl-35012686
BACKGROUND: The tomographic finding, which has been called the "fingerprint sign" in en face reconstructions, seems to be the result of a variety of processes that cause distension of the outer plexiform layer (OPL) and the Henle fiber layer (HFL). The aim of this paper is to describe the appearance of concentric rings at the OPL/HFL interface visualized using en face reconstructions of cross-sectional optical coherence tomography images of patients with Vogt-Koyanagi-Harada disease. METHODS: Retrospective analysis of images of six eyes of three patients obtained by cross-sectional OCT imaging and en face reconstruction at the level of the OPL/HFL interface. RESULTS: All eyes presented with a dentate or saw-tooth pattern of the OPL/HFL interface on cross-sectional OCT with corresponding concentric rings on en face OCT reconstruction, consistent with the recently published "fingerprint sign". Initial OPL/HFL interface changes were observed between the first and fourth months after treatment and resolution of VKHD associated serous retinal detachments. These OPL/HFL interface changes have persisted for many years following the resolution of the active inflammation. CONCLUSIONS: Changes in the OPL/HFL interface can be identified following successful treatment of VKHD. These included both a dentate or saw-tooth pattern on cross-sectional imaging and concentric rings or the "fingerprint sign" on en face reconstructions. These changes persisted for many years despite disease quiescence.
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Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Año: 2022 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Año: 2022 Tipo del documento: Article