Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1<i>H</i>)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90.

Larghi, Enrique L; Bruneau, Alexandre; Sauvage, Félix; Alami, Mouad; Vergnaud-Gauduchon, Juliette; Messaoudi, Samir

Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1H)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90.

Larghi, Enrique L; Bruneau, Alexandre; Sauvage, Félix; Alami, Mouad; Vergnaud-Gauduchon, Juliette; Messaoudi, Samir.

Larghi EL; CNRS, BioCIS, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
Bruneau A; Instituto de Química Rosario (IQUIR) CONICET/UNR, FBioyF, Rosario S2002LRK, Argentina.
Sauvage F; Instituto de Química Rosario (IQUIR) CONICET/UNR, FBioyF, Rosario S2002LRK, Argentina.
Alami M; CNRS, Institut Galien-Paris Saclay, Université Paris-Saclay, 92296 Châtenay-Malabry, France.
Vergnaud-Gauduchon J; CNRS, BioCIS, Université Paris-Saclay, 92290 Châtenay-Malabry, France.
Messaoudi S; CNRS, Institut Galien-Paris Saclay, Université Paris-Saclay, 92296 Châtenay-Malabry, France.

Molecules ; 27(2)2022 Jan 09.

Article en En | MEDLINE | ID: mdl-35056725

Asunto(s)

Proteínas HSP90 de Choque Térmico

Palabras clave

3-(heteroaryl)quinolin-2(1H)-ones; 6BrCaQ; Hsp90; cytotoxicity; purines

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas HSP90 de Choque Térmico Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas HSP90 de Choque Térmico Idioma: En Año: 2022 Tipo del documento: Article