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A Tissue Adhesion-Controllable and Biocompatible Small-Scale Hydrogel Adhesive Robot.
Lee, Yun-Woo; Chun, Sungwoo; Son, Donghoon; Hu, Xinghao; Schneider, Martina; Sitti, Metin.
  • Lee YW; Physical Intelligence Department, Max Planck Institute for Intelligent System, 70569, Stuttgart, Germany.
  • Chun S; Physical Intelligence Department, Max Planck Institute for Intelligent System, 70569, Stuttgart, Germany.
  • Son D; Department of Electronics and Information Engineering, Korea University, Sejong, 30019, Republic of Korea.
  • Hu X; Physical Intelligence Department, Max Planck Institute for Intelligent System, 70569, Stuttgart, Germany.
  • Schneider M; School of Mechanical Engineering, Pusan National University, Busan, 46241, Republic of Korea.
  • Sitti M; Physical Intelligence Department, Max Planck Institute for Intelligent System, 70569, Stuttgart, Germany.
Adv Mater ; 34(13): e2109325, 2022 Apr.
Article en En | MEDLINE | ID: mdl-35060215
ABSTRACT
Recently, the realization of minimally invasive medical interventions on targeted tissues using wireless small-scale medical robots has received an increasing attention. For effective implementation, such robots should have a strong adhesion capability to biological tissues and at the same time easy controlled detachment should be possible, which has been challenging. To address such issue, a small-scale soft robot with octopus-inspired hydrogel adhesive (OHA) is proposed. Hydrogels of different Young's moduli are adapted to achieve a biocompatible adhesive with strong wet adhesion by preventing the collapse of the octopus-inspired patterns during preloading. Introduction of poly(N-isopropylacrylamide) hydrogel for dome-like protuberance structure inside the sucker wall of polyethylene glycol diacrylate hydrogel provides a strong tissue attachment in underwater and at the same time enables easy detachment by temperature changes due to its temperature-dependent volume change property. It is finally demonstrated that the small-scale soft OHA robot can efficiently implement biomedical functions owing to strong adhesion and controllable detachment on biological tissues while operating inside the body. Such robots with repeatable tissue attachment and detachment possibility pave the way for future wireless soft miniature robots with minimally invasive medical interventions.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Robótica / Hidrogeles Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Robótica / Hidrogeles Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article