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Lipopolysaccharide induces acute lung injury and alveolar haemorrhage in association with the cytokine storm, coagulopathy and AT1R/JAK/STAT augmentation in a rat model that mimics moderate and severe Covid-19 pathology.
Al-Ani, Bahjat; ShamsEldeen, Asmaa M; Kamar, Samaa S; Haidara, Mohamed A; Al-Hashem, Fahaid; Alshahrani, Mohammad Y; Al-Hakami, Ahmed M; Kader, Dina H Abdel; Maarouf, Amro.
  • Al-Ani B; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
  • ShamsEldeen AM; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Kamar SS; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Haidara MA; Department of Physiology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Al-Hashem F; Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
  • Alshahrani MY; Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha, Saudi Arabia.
  • Al-Hakami AM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
  • Kader DHA; Department of Microbiology and Clinical Parasitology, College of Medicine, King Khalid University, Abha, Saudi Arabia.
  • Maarouf A; Department of Medical Histology, Kasr Al-Aini Faculty of Medicine, Cairo University, Cairo, Egypt.
Clin Exp Pharmacol Physiol ; 49(4): 483-491, 2022 04.
Article en En | MEDLINE | ID: mdl-35066912
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastornos de la Coagulación Sanguínea / Transducción de Señal / Lipopolisacáridos / Receptor de Angiotensina Tipo 1 / Factores de Transcripción STAT / Lesión Pulmonar Aguda / Síndrome de Liberación de Citoquinas / COVID-19 / Hemorragia / Enfermedades Pulmonares Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trastornos de la Coagulación Sanguínea / Transducción de Señal / Lipopolisacáridos / Receptor de Angiotensina Tipo 1 / Factores de Transcripción STAT / Lesión Pulmonar Aguda / Síndrome de Liberación de Citoquinas / COVID-19 / Hemorragia / Enfermedades Pulmonares Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article