Mice with monoallelic <i>GNAO1</i> loss exhibit reduced inhibitory synaptic input to cerebellar Purkinje cells.

Feng, Huijie; Yuan, Yukun; Williams, Michael R; Roy, Alex J; Leipprandt, Jeffery R; Neubig, Richard R

Mice with monoallelic GNAO1 loss exhibit reduced inhibitory synaptic input to cerebellar Purkinje cells.

Feng, Huijie; Yuan, Yukun; Williams, Michael R; Roy, Alex J; Leipprandt, Jeffery R; Neubig, Richard R.

Feng H; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, Michigan.
Yuan Y; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, Michigan.
Williams MR; Department of Pediatrics and Human Development, Michigan State University, Grand Rapids, Michigan.
Roy AJ; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, Michigan.
Leipprandt JR; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, Michigan.
Neubig RR; Department of Pharmacology & Toxicology, Michigan State University, East Lansing, Michigan.

J Neurophysiol ; 127(3): 607-622, 2022 03 01.

Article en En | MEDLINE | ID: mdl-35080448

Asunto(s)

Trastornos del Movimiento; Células de Purkinje; Animales; Cerebelo/fisiología; Subunidades alfa de la Proteína de Unión al GTP Gi-Go/genética; Subunidades alfa de la Proteína de Unión al GTP Gi-Go/metabolismo; Ratones; Células de Purkinje/fisiología; Transmisión Sináptica/fisiología; Ácido gamma-Aminobutírico/metabolismo

Palabras clave

GNAO1; Purkinje cells; cerebellum; movement disorder

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células de Purkinje / Trastornos del Movimiento Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

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