Clinical Outcome and Underlying Genetic Cause of Functional Terminal Complement Pathway Deficiencies in a Multicenter UK Cohort.

Shears, Annalie; Steele, Cathal; Craig, Jamie; Jolles, Stephen; Savic, Sinisa; Hague, Rosie; Coulter, Tanya; Herriot, Richard; Arkwright, Peter D

Shears, Annalie; Steele, Cathal; Craig, Jamie; Jolles, Stephen; Savic, Sinisa; Hague, Rosie; Coulter, Tanya; Herriot, Richard; Arkwright, Peter D.

Shears A; NIHR Paediatric Academic Clinical Fellow, University of Manchester, Manchester, UK.
Steele C; NHS Tayside, Ninewells Hospital and Medical School, Dundee, Scotland.
Craig J; University of Dundee, Dundee, Scotland.
Jolles S; University Hospital of Wales, Cardiff, Wales.
Savic S; School of Medicine, University of Leeds, Leeds, & NIHR-BRC, Leeds, UK.
Hague R; Immunology, Royal Hospital for Children, Glasgow, Scotland.
Coulter T; Immunology, Belfast Health and Social Care Trust, Belfast, Northern Ireland.
Herriot R; Immunology, Aberdeen Royal Infirmary, Aberdeen, Scotland.
Arkwright PD; Paediatric Immunology, Lydia Becker Institute, University of Manchester, Manchester, UK. peter.arkwright@nhs.net.

J Clin Immunol ; 42(3): 665-671, 2022 04.

Article en En | MEDLINE | ID: mdl-35084692

Asunto(s)

COVID-19; Infecciones Meningocócicas; Sepsis; Adolescente; Adulto; Niño; Preescolar; Estudios de Cohortes; Proteínas del Sistema Complemento/genética; Enfermedades por Deficiencia de Complemento Hereditario; Humanos; Infecciones Meningocócicas/genética; Persona de Mediana Edad; Reino Unido/epidemiología; Adulto Joven

Palabras clave

Factor H; Factor I; Genetics; Meningococcal infection; Terminal complement pathway

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sepsis / COVID-19 / Infecciones Meningocócicas Tipo de estudio: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Child, preschool / Humans / Middle aged País como asunto: Europa Idioma: En Año: 2022 Tipo del documento: Article

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