Why are people still dying of drug-susceptible TB in Paris in the 21st century?
Int J Tuberc Lung Dis
; 26(2): 142-149, 2022 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-35086626
ABSTRACT
BACKGROUND:
Although the burden of TB is lower in France than in low-income countries, patients continue to die from TB in Paris. Our goal was to describe TB-related deaths and to identify associated risk factors.METHODS:
We conducted a retrospective cohort study in two hospitals in Paris between 2013 and 2018. All patients with drug-susceptible TB were included and followed until end of treatment. The primary outcome was death. We performed univariate and multivariate analysis using Cox proportional hazard model.RESULTS:
Of the 523 patients included, 362 were men (median age 37 years), of whom 24 patients died (4.5%). The final survival model concluded that age (HR 1.1 for each additional year), not living in one´s own accommodation (HR 5.9), being born in France (HR 8.0), being alcoholic (HR 4.2), having a history of cancer (HR 7.1) or meningeal or miliary TB (HR 8.2) were associated with a higher risk of death.CONCLUSION:
The rate of TB-associated death is unacceptably high for a curable disease. To note, patients born in France were much more at risk of death than immigrants. We believe raising awareness among healthcare professionals is a potentially easy and efficient lever for improving care.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis Miliar
/
Emigrantes e Inmigrantes
Tipo de estudio:
Etiology_studies
/
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adult
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Humans
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Male
País como asunto:
Europa
Idioma:
En
Año:
2022
Tipo del documento:
Article