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Discovery of an insulin-induced gene binding compound that ameliorates nonalcoholic steatohepatitis by inhibiting sterol regulatory element-binding protein-mediated lipogenesis.
Jiang, Shi-You; Yang, Xinglin; Yang, Zimo; Li, Jue-Wan; Xu, Meng-Qiang; Qu, Yu-Xiu; Tang, Jing-Jie; Li, Yun-Feng; Wang, Liguo; Shao, Yi-Wen; Meng, Xin-Yuan; Hu, Huili; Song, Bao-Liang; Rao, Yu; Qi, Wei.
  • Jiang SY; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China.
  • Yang X; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Yang Z; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
  • Li JW; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
  • Xu MQ; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Qu YX; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Tang JJ; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Li YF; The State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Wang L; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, China.
  • Shao YW; MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, China.
  • Meng XY; The Key Laboratory of Experimental Teratology, Ministry of Education and Department of Molecular Medicine and Genetics, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Jinan, China.
  • Hu H; The Research Center of Stem Cell and Regenerative Medicine, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Jinan, China.
  • Song BL; The Key Laboratory of Experimental Teratology, Ministry of Education and Department of Molecular Medicine and Genetics, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Jinan, China.
  • Rao Y; The Research Center of Stem Cell and Regenerative Medicine, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Jinan, China.
  • Qi W; The Key Laboratory of Experimental Teratology, Ministry of Education and Department of Molecular Medicine and Genetics, Shandong University Cheeloo Medical College, School of Basic Medical Sciences, Jinan, China.
Hepatology ; 76(5): 1466-1481, 2022 11.
Article en En | MEDLINE | ID: mdl-35102596
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Insulinas / Enfermedad del Hígado Graso no Alcohólico Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Insulinas / Enfermedad del Hígado Graso no Alcohólico Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article