Immunoregulatory effects of glioma-associated stem cells on the glioblastoma peritumoral microenvironment: a differential PD-L1 expression from core to periphery?

Menna, Grazia; Manini, Ivana; Cesselli, Daniela; Skrap, Miran; Olivi, Alessandro; Ius, Tamara; Della Pepa, Giuseppe Maria

Menna, Grazia; Manini, Ivana; Cesselli, Daniela; Skrap, Miran; Olivi, Alessandro; Ius, Tamara; Della Pepa, Giuseppe Maria.

Menna G; 1Institute of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome.
Manini I; 2Institute of Pathology, University Hospital, Udine; and.
Cesselli D; 2Institute of Pathology, University Hospital, Udine; and.
Skrap M; 3Neurosurgery Unit, Department of Neuroscience, Santa Maria della Misericordia, University Hospital, Udine, Italy.
Olivi A; 1Institute of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome.
Ius T; 3Neurosurgery Unit, Department of Neuroscience, Santa Maria della Misericordia, University Hospital, Udine, Italy.
Della Pepa GM; 1Institute of Neurosurgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Catholic University, Rome.

Neurosurg Focus ; 52(2): E4, 2022 02.

Article en En | MEDLINE | ID: mdl-35104793

Asunto(s)

Neoplasias Encefálicas; Glioblastoma; Glioma; Antígeno B7-H1/metabolismo; Glioblastoma/cirugía; Glioma/patología; Glioma/cirugía; Humanos; Inmunidad; Células Madre; Microambiente Tumoral

Palabras clave

5-ALA; PD-1; PD-L1; glioblastoma; glioma-associated stem cells; immunotherapy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Glioma Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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