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Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity.
Meng, Bo; Abdullahi, Adam; Ferreira, Isabella A T M; Goonawardane, Niluka; Saito, Akatsuki; Kimura, Izumi; Yamasoba, Daichi; Gerber, Pehuén Pereyra; Fatihi, Saman; Rathore, Surabhi; Zepeda, Samantha K; Papa, Guido; Kemp, Steven A; Ikeda, Terumasa; Toyoda, Mako; Tan, Toong Seng; Kuramochi, Jin; Mitsunaga, Shigeki; Ueno, Takamasa; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Brevini, Teresa; Mallery, Donna L; Charles, Oscar J; Bowen, John E; Joshi, Anshu; Walls, Alexandra C; Jackson, Laurelle; Martin, Darren; Smith, Kenneth G C; Bradley, John; Briggs, John A G; Choi, Jinwook; Madissoon, Elo; Meyer, Kerstin B; Mlcochova, Petra; Ceron-Gutierrez, Lourdes; Doffinger, Rainer; Teichmann, Sarah A; Fisher, Andrew J; Pizzuto, Matteo S; de Marco, Anna; Corti, Davide; Hosmillo, Myra; Lee, Joo Hyeon; James, Leo C; Thukral, Lipi; Veesler, David; Sigal, Alex; Sampaziotis, Fotios.
  • Meng B; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Abdullahi A; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Ferreira IATM; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Goonawardane N; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Saito A; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Kimura I; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Yamasoba D; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Gerber PP; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Fatihi S; Department of Veterinary Science, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan.
  • Rathore S; Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Zepeda SK; Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Papa G; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Kemp SA; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Ikeda T; CSIR Institute of Genomics and Integrative Biology, Delhi, India.
  • Toyoda M; CSIR Institute of Genomics and Integrative Biology, Delhi, India.
  • Tan TS; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Kuramochi J; MRC-Laboratory of Molecular Biology, Cambridge, UK.
  • Mitsunaga S; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Ueno T; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Shirakawa K; Division of Molecular Virology and Genetics, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
  • Takaori-Kondo A; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
  • Brevini T; Division of Infection and Immunity, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
  • Mallery DL; Kuramochi Clinic Interpark, Utsunomiya, Japan.
  • Charles OJ; Human Genetics Laboratory, National Institute of Genetics, Mishima, Japan.
  • Bowen JE; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Joshi A; MRC-Laboratory of Molecular Biology, Cambridge, UK.
  • Walls AC; Division of Infection and Immunity, UCL, London, UK.
  • Bradley J; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Briggs JAG; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Choi J; Department of Biochemistry, University of Washington, Seattle, WA, USA.
  • Madissoon E; Department of Virology, University of Cambridge, Cambridge, UK.
  • Meyer KB; Africa Health Research Institute, Durban, South Africa.
  • Mlcochova P; University of Cape Town, Cape Town, South Africa.
  • Ceron-Gutierrez L; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • Doffinger R; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Teichmann SA; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Fisher AJ; Max Planck Institute of Biochemistry, Martinsried, Germany.
  • Pizzuto MS; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, UK.
  • de Marco A; Welcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Corti D; European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, UK.
  • Hosmillo M; Welcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Lee JH; Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Cambridge, UK.
  • James LC; Department of Medicine, University of Cambridge, Cambridge, UK.
  • Thukral L; Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK.
  • Veesler D; Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, UK.
  • Sigal A; Welcome Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Sampaziotis F; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, UK.
Nature ; 603(7902): 706-714, 2022 03.
Article en En | MEDLINE | ID: mdl-35104837
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Serina Endopeptidasas / Internalización del Virus / SARS-CoV-2 / COVID-19 / Fusión de Membrana Límite: Aged80 Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Serina Endopeptidasas / Internalización del Virus / SARS-CoV-2 / COVID-19 / Fusión de Membrana Límite: Aged80 Idioma: En Año: 2022 Tipo del documento: Article