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Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-ß1/Smad3 pathway.
Zhang, Wenying; Rong, Guang; Gu, Jinge; Fan, Cuiling; Guo, Tingting; Jiang, Tingting; Deng, Weiqian; Xie, Jiayu; Su, Zhihua; Yu, Qimin; Mai, Jingyi; Zheng, Rinan; Chen, Xingling; Tang, Xun; Zhang, Jun.
  • Zhang W; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Rong G; Department of Nephrology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Gu J; Department of Nephrology, SSL Central Hospital of Dongguan City, Dongguan, China.
  • Fan C; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Guo T; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Jiang T; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Deng W; Department of Nephrology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
  • Xie J; Department of Nephrology, Fifth Affiliated Hospital of Southern Medical University, Guangzhou, China.
  • Su Z; Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of Neurosurgery, Zhujiang Hospital, The National Key Clinical Specialty, The Neurosurgery Institute of Guangdong Province, The Engineering Technology Research Center of Education Ministry of China, Southern Med
  • Yu Q; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Mai J; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Zheng R; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Chen X; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Tang X; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Zhang J; Department of Nephrology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
FASEB J ; 36(3): e22084, 2022 03.
Article en En | MEDLINE | ID: mdl-35107844
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis / Transducción de Señal / Niacinamida / Insuficiencia Renal Crónica / Nicotinamida N-Metiltransferasa / Proteína smad3 / Factor de Crecimiento Transformador beta1 Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fibrosis / Transducción de Señal / Niacinamida / Insuficiencia Renal Crónica / Nicotinamida N-Metiltransferasa / Proteína smad3 / Factor de Crecimiento Transformador beta1 Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article