Natalizumab treatment during pregnancy in multiple sclerosis-clinical and bioethical aspects of an ongoing debate.
Wien Med Wochenschr
; 172(15-16): 373-378, 2022 Nov.
Article
en En
| MEDLINE
| ID: mdl-35142953
ABSTRACT
BACKGROUND:
Natalizumab is an approved treatment for relapsing remitting multiple sclerosis; however, its safety during pregnancy is not formally proven. CASE PRESENTATION We report a woman with multiple sclerosis being treated with natalizumab before pregnancy. After withdrawal of natalizumab, she suffered a severe, disabling rebound. In agreement with the patient, natalizumab was restarted during pregnancy. Our patient improved substantially and gave birth to a healthy boy.CONCLUSION:
Use of natalizumab during pregnancy may be an option in highly active multiple sclerosis.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Esclerosis Múltiple Recurrente-Remitente
/
Esclerosis Múltiple
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
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Male
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Pregnancy
Idioma:
En
Año:
2022
Tipo del documento:
Article