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CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade.
Tong, Jingshan; Tan, Xiao; Song, Xiangping; Gao, Man; Risnik, Denise; Hao, Suisui; Ermine, Kaylee; Wang, Peng; Li, Hua; Huang, Yi; Yu, Jian; Zhang, Lin.
  • Tong J; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
  • Tan X; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Song X; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
  • Gao M; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Risnik D; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
  • Hao S; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Ermine K; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
  • Wang P; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Li H; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
  • Huang Y; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Yu J; UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.
  • Zhang L; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Cancer Res ; 82(7): 1340-1352, 2022 04 01.
Article en En | MEDLINE | ID: mdl-35149588
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinasa 4 Dependiente de la Ciclina / Quinasa 6 Dependiente de la Ciclina / Ligando Inductor de Apoptosis Relacionado con TNF / Receptores del Ligando Inductor de Apoptosis Relacionado con TNF / Proteína Tumoral p73 / Inhibidores de Puntos de Control Inmunológico Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Quinasa 4 Dependiente de la Ciclina / Quinasa 6 Dependiente de la Ciclina / Ligando Inductor de Apoptosis Relacionado con TNF / Receptores del Ligando Inductor de Apoptosis Relacionado con TNF / Proteína Tumoral p73 / Inhibidores de Puntos de Control Inmunológico Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article