Lateralization as a symphony: Joint influence of interhemispheric inhibition and transmission on brain asymmetry and syntactic processing.

ABSTRACT

This study investigated the roles of cross-hemispheric communications in promoting left-lateralized syntactic processing in the brain. Fifty-six young right-handers without familial sinistrality background underwent a divided visual field ERP grammaticality judgment experiment to assess syntactic processing in each hemisphere. Two behavioral tasks -the bilateral flanker task and bilateral word matching task, were used to assess cross-hemispheric inhibition and transmission. Grand average ERP data showed a significant P600 grammaticality effect in the left hemisphere (LH) only; however, individual variations in the P600 responses were observed in both hemispheres. Results of correlational analyses showed that larger LH P600 effects were associated with slower inter-hemispheric transmissions; smaller right hemisphere (RH) P600 effects were associated with more effective RH inhibition. These results yielded support for both the callosal distance hypothesis and the inhibition hypothesis for language lateralization and demonstrated that different aspects of cross-hemispheric communications jointly influence the degree of syntactic lateralization.