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In Vitro-In Vivo Correlation of Blood-Brain Barrier Permeability of Drugs: A Feasibility Study Towards Development of Prediction Methods for Brain Drug Concentration in Humans.
Ito, Ryo; Morio, Hanae; Baba, Tomoyo; Sakaguchi, Yasuyuki; Wakayama, Naomi; Isogai, Ryuto; Yamaura, Yoshiyuki; Komori, Takafumi; Furihata, Tomomi.
  • Ito R; Research Center of Neurology, Ono Pharmaceutical Co., Ltd., Osaka, Japan.
  • Morio H; Laboratory of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
  • Baba T; Laboratory of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
  • Sakaguchi Y; Laboratory of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
  • Wakayama N; Global Drug Metabolism and Pharmacokinetics Tsukuba, Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki, Japan.
  • Isogai R; Laboratory of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
  • Yamaura Y; Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co., Ltd., Osaka, Japan.
  • Komori T; Global Drug Metabolism and Pharmacokinetics Tsukuba, Tsukuba Research Laboratories, Eisai Co., Ltd., Ibaraki, Japan.
  • Furihata T; Laboratory of Clinical Pharmacy & Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo, 192-0392, Japan. tomomif@toyaku.ac.jp.
Pharm Res ; 39(7): 1575-1586, 2022 Jul.
Article en En | MEDLINE | ID: mdl-35288803
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Encéfalo / Barrera Hematoencefálica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Encéfalo / Barrera Hematoencefálica Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article