Carajurin Induces Apoptosis in <i>Leishmania amazonensis</i> Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction.

Silva-Silva, João Victor; Moragas-Tellis, Carla J; Chagas, Maria S S; Souza, Paulo Victor R; Moreira, Davyson L; Hardoim, Daiana J; Taniwaki, Noemi N; Costa, Vanessa F A; Bertho, Alvaro L; Brondani, Daniela; Zapp, Eduardo; de Oliveira, Aldo Sena; Calabrese, Kátia S; Behrens, Maria D; Almeida-Souza, Fernando

Carajurin Induces Apoptosis in Leishmania amazonensis Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction.

Silva-Silva, João Victor; Moragas-Tellis, Carla J; Chagas, Maria S S; Souza, Paulo Victor R; Moreira, Davyson L; Hardoim, Daiana J; Taniwaki, Noemi N; Costa, Vanessa F A; Bertho, Alvaro L; Brondani, Daniela; Zapp, Eduardo; de Oliveira, Aldo Sena; Calabrese, Kátia S; Behrens, Maria D; Almeida-Souza, Fernando.

Silva-Silva JV; Laboratory of Immunomodulation and Protozoology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Moragas-Tellis CJ; Laboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Chagas MSS; Laboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Souza PVR; Laboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Moreira DL; Postgraduate Program in Translational Research in Drugs and Medicines, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Hardoim DJ; Laboratory of Natural Products for Public Health, Pharmaceutical Technology Institute, Farmanguinhos, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Taniwaki NN; Laboratory of Immunomodulation and Protozoology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Costa VFA; Electron Microscopy Nucleus, Adolfo Lutz Institute, Sao Paulo 01246-000, Brazil.
Bertho AL; Laboratory of Immunoparasitology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Brondani D; Laboratory of Immunoparasitology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
Zapp E; Flow Cytometry Technological Platform, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.
de Oliveira AS; Research Group on Medicinal and Biological Chemistry (GPQMedBio), Department of Exact Sciences and Education, Federal University of Santa Catarina, Blumenau 89036-002, Brazil.
Calabrese KS; Research Group on Medicinal and Biological Chemistry (GPQMedBio), Department of Exact Sciences and Education, Federal University of Santa Catarina, Blumenau 89036-002, Brazil.
Behrens MD; Research Group on Medicinal and Biological Chemistry (GPQMedBio), Department of Exact Sciences and Education, Federal University of Santa Catarina, Blumenau 89036-002, Brazil.
Almeida-Souza F; Laboratory of Immunomodulation and Protozoology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro 21040-900, Brazil.