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Molecular imaging of endocrine neoplasms with emphasis on 18F-DOPA PET: a practical approach for well-tailored imaging protocols.
Fargette, Christelle; Imperiale, Alessio; Taïeb, David.
  • Fargette C; Department of Nuclear Medicine, CERIMED, La Timone University Hospital, Aix-Marseille University, Marseille, France.
  • Imperiale A; Department of Nuclear Medicine and Molecular Imaging, Institut de Cancérologie de Strasbourg Europe (ICANS), IPHC, UMR 7178, University Hospitals of Strasbourg, CNRS/University of Strasbourg, Strasbourg, France.
  • Taïeb D; Department of Nuclear Medicine, CERIMED, La Timone University Hospital, Aix-Marseille University, Marseille, France - david.taieb@ap-hm.fr.
Q J Nucl Med Mol Imaging ; 66(2): 141-147, 2022 Jun.
Article en En | MEDLINE | ID: mdl-35343670
ABSTRACT
6-[18F]-L-fluoro-L-3, 4-dihydroxyphenylalanine (18F-DOPA) PET/CT can be a useful tool for the detection of different neuroendocrine tumors (NETs). The main determinants of 18F-DOPA uptake and retention by NETs are related to expression of LAT1/LAT2 transporters, expression and activity of AADC and biochemical phenotype, all being intimately inter-connected to their embryological origin. In order to improve sensitivity of 18F-DOPA PET, it is of main importance to perform indivisualized imaging protocols across primaries. This review provides a practical approach for performing well-tailored imaging protocols and describes the clinical value of the recommended radiopharmaceuticals.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tumores Neuroendocrinos / Neoplasias de las Glándulas Suprarrenales Tipo de estudio: Guideline Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tumores Neuroendocrinos / Neoplasias de las Glándulas Suprarrenales Tipo de estudio: Guideline Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article