NEDD4 attenuates phosgene-induced acute lung injury through the inhibition of Notch1 activation.

Shao, Yiru; Jiang, Zhifeng; He, Daikun; Shen, Jie

Shao, Yiru; Jiang, Zhifeng; He, Daikun; Shen, Jie.

Shao Y; Center of Emergency & Intensive Care Unit, Jinshan Hospital, Fudan University, Shanghai, China.
Jiang Z; Key Laboratory of Chemical Injury, Emergency and Critical Medicine of Shanghai Municipal Health Commission, Shanghai, China.
He D; Medical Research Center for Chemical Injury, Emergency and Critical Care of Chemical Injury, Jinshan Hospital, Fudan University, Shanghai, China.
Shen J; Center of Emergency & Intensive Care Unit, Jinshan Hospital, Fudan University, Shanghai, China.

J Cell Mol Med ; 26(10): 2831-2840, 2022 05.

Article en En | MEDLINE | ID: mdl-35355403

Asunto(s)

Lesión Pulmonar Aguda; Ubiquitina-Proteína Ligasas Nedd4; Fosgeno; Receptor Notch1; Lesión Pulmonar Aguda/inducido químicamente; Lesión Pulmonar Aguda/genética; Lesión Pulmonar Aguda/metabolismo; Animales; Líquido del Lavado Bronquioalveolar; Inflamación/metabolismo; Pulmón/metabolismo; Ubiquitina-Proteína Ligasas Nedd4/genética; Ubiquitina-Proteína Ligasas Nedd4/metabolismo; Fosgeno/toxicidad; Ratas; Ratas Sprague-Dawley; Receptor Notch1/genética; Receptor Notch1/metabolismo

Palabras clave

NEDD4; Notch1; phosgene; pulmonary inflammation

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosgeno / Receptor Notch1 / Lesión Pulmonar Aguda / Ubiquitina-Proteína Ligasas Nedd4 Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google