Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway.

Shen, Wei; Tong, Dimin; Chen, Jie; Li, Hongxiang; Hu, Zeyang; Xu, Shuguang; He, Sufang; Ge, Zhen; Zhang, Jianan; Mao, Qiqi; Chen, Hang; Xu, Guodong

Shen, Wei; Tong, Dimin; Chen, Jie; Li, Hongxiang; Hu, Zeyang; Xu, Shuguang; He, Sufang; Ge, Zhen; Zhang, Jianan; Mao, Qiqi; Chen, Hang; Xu, Guodong.

Shen W; Department of Pulmonary and Critical Care Medicine, The Third People's Hospital of Cixi, Ningbo, Zhejiang, China.
Tong D; Department of Pulmonary and Critical Care Medicine, The Third People's Hospital of Cixi, Ningbo, Zhejiang, China.
Chen J; Department of Pulmonary and Critical Care Medicine, The Third People's Hospital of Cixi, Ningbo, Zhejiang, China.
Li H; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Hu Z; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Xu S; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
He S; Department of Pulmonary and Critical Care Medicine, Guangdong Provincial People's Hospital Ganzhou Hospital, Ganzhou, Jiangxi, China.
Ge Z; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Zhang J; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Mao Q; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Chen H; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.
Xu G; Department of Cardiothoracic Surgery, The Affiliated Lihuili Hospital, Ningbo University, Ningbo, Zhejiang, China.

J Clin Lab Anal ; 36(5): e24396, 2022 May.

Article en En | MEDLINE | ID: mdl-35373420

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales; Adenocarcinoma del Pulmón; Carcinoma de Pulmón de Células no Pequeñas; Proteínas de Ciclo Celular; Neoplasias Pulmonares; Proteínas Adaptadoras Transductoras de Señales/genética; Adenocarcinoma del Pulmón/genética; Adenocarcinoma del Pulmón/patología; Apoptosis/genética; Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/patología; Ciclo Celular/genética; Proteínas de Ciclo Celular/genética; Línea Celular Tumoral; Proliferación Celular; Fase G1; Regulación Neoplásica de la Expresión Génica; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patología; Oncogenes; Transducción de Señal/genética; Proteína p53 Supresora de Tumor/genética; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

CDCA5; G1 phase arrest; apoptosis; bioinformatics analyses; non-small cell lung cancer

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Proteínas de Ciclo Celular / Proteínas Adaptadoras Transductoras de Señales / Adenocarcinoma del Pulmón / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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