Mechanistic insights into the C<sub>55</sub>-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures.

Wood, Thomas M; Zeronian, Matthieu R; Buijs, Ned; Bertheussen, Kristine; Abedian, Hanieh K; Johnson, Aidan V; Pearce, Nicholas M; Lutz, Martin; Kemmink, Johan; Seirsma, Tjalling; Hamoen, Leendert W; Janssen, Bert J C; Martin, Nathaniel I

Mechanistic insights into the C₅₅-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures.

Wood, Thomas M; Zeronian, Matthieu R; Buijs, Ned; Bertheussen, Kristine; Abedian, Hanieh K; Johnson, Aidan V; Pearce, Nicholas M; Lutz, Martin; Kemmink, Johan; Seirsma, Tjalling; Hamoen, Leendert W; Janssen, Bert J C; Martin, Nathaniel I.

Wood TM; Biological Chemistry Group, Institute of Biology Leiden, Leiden University Sylviusweg 72 2333 BE Leiden The Netherlands n.i.martin@biology.leidenuniv.nl.
Zeronian MR; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University Universiteitsweg 99 3584 CG Utrecht The Netherlands.
Buijs N; Structural Biochemistry, Bijvoet Centre for Biomolecular Research, Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands b.j.c.janssen@uu.nl.
Bertheussen K; Biological Chemistry Group, Institute of Biology Leiden, Leiden University Sylviusweg 72 2333 BE Leiden The Netherlands n.i.martin@biology.leidenuniv.nl.
Abedian HK; Biological Chemistry Group, Institute of Biology Leiden, Leiden University Sylviusweg 72 2333 BE Leiden The Netherlands n.i.martin@biology.leidenuniv.nl.
Johnson AV; Biological Chemistry Group, Institute of Biology Leiden, Leiden University Sylviusweg 72 2333 BE Leiden The Netherlands n.i.martin@biology.leidenuniv.nl.
Pearce NM; Biological Chemistry Group, Institute of Biology Leiden, Leiden University Sylviusweg 72 2333 BE Leiden The Netherlands n.i.martin@biology.leidenuniv.nl.
Lutz M; Structural Biochemistry, Bijvoet Centre for Biomolecular Research, Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands b.j.c.janssen@uu.nl.
Kemmink J; Structural Biochemistry, Bijvoet Centre for Biomolecular Research, Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands b.j.c.janssen@uu.nl.
Seirsma T; Faculty of Science and Engineering, University of Groningen 9747 AG Groningen The Netherlands.
Hamoen LW; Bacterial Cell Biology and Physiology Group, Swammerdam Institute for Life Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.
Janssen BJC; Bacterial Cell Biology and Physiology Group, Swammerdam Institute for Life Sciences, University of Amsterdam Science Park 904 1098 XH Amsterdam The Netherlands.
Martin NI; Structural Biochemistry, Bijvoet Centre for Biomolecular Research, Utrecht University Padualaan 8 3584 CH Utrecht The Netherlands b.j.c.janssen@uu.nl.

Chem Sci ; 13(10): 2985-2991, 2022 Mar 09.

Article en En | MEDLINE | ID: mdl-35382464

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2022 Tipo del documento: Article