Beta 2-microglobulin: a prognostic parameter for graft survival after renal transplantation.
Immunobiology
; 173(1): 56-62, 1986 Oct.
Article
en En
| MEDLINE
| ID: mdl-3542811
ABSTRACT
The determination of beta 2-microglobulin has recently been proposed as a promising diagnostic method to monitor the state of renal allografts. Elevated levels of beta 2MG in the serum and/or urine allow the substantiation of the diagnosis of an acute graft rejection and are helpful in distinguishing acute tubular necrosis from a rejection reaction. In this paper, the usefulness of beta 2MG serum levels is evaluated, not only during the immediate post-operation phase but also for the long-term prognosis of renal allografts. The immunosuppression treatment included methylprednisolone and azathioprine in all the presented patients. The data indicate that a rapid normalization of beta 2MGSL within 6 days, even if the decrease is interrupted by re-elevation due to acute rejection episodes or inflammatory diseases, represents a good long-term prognosis for kidney allografts.
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Banco de datos:
MEDLINE
Asunto principal:
Microglobulina beta-2
/
Trasplante de Riñón
/
Supervivencia de Injerto
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
1986
Tipo del documento:
Article