MiR-708-5p/Pit-1 axis mediates high phosphate-induced calcification in vascular smooth muscle cells via Wnt8b/ß-catenin pathway.

Wu, Na; Liu, Guo-Bing; Zhang, Yu-Min; Wang, Yong; Zeng, Hai-Tao; Xiang, Hui

Wu, Na; Liu, Guo-Bing; Zhang, Yu-Min; Wang, Yong; Zeng, Hai-Tao; Xiang, Hui.

Wu N; Department of Cardiology, The Third Hospital of Changsha, Changsha, China.
Liu GB; Department of Cardiology, The Third Hospital of Changsha, Changsha, China.
Zhang YM; Department of Cardiology, The Third Hospital of Changsha, Changsha, China.
Wang Y; Department of Cardiology, The Third Hospital of Changsha, Changsha, China.
Zeng HT; Department of Cardiology, The Third Hospital of Changsha, Changsha, China.
Xiang H; Department of Nephrology, The Third Hospital of Changsha, Changsha, China.

Kaohsiung J Med Sci ; 38(7): 653-661, 2022 Jul.

Article en En | MEDLINE | ID: mdl-35460325

Asunto(s)

MicroARNs; Factor de Transcripción Pit-1/metabolismo; Calcificación Vascular; Fosfatasa Alcalina/genética; Fosfatasa Alcalina/metabolismo; Glucógeno Sintasa Quinasa 3 beta/genética; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Humanos; MicroARNs/genética; MicroARNs/metabolismo; Músculo Liso Vascular/metabolismo; Fosfatos/efectos adversos; Fosfatos/metabolismo; Calcificación Vascular/inducido químicamente; Calcificación Vascular/genética; Proteínas Wnt/metabolismo; Vía de Señalización Wnt/genética; beta Catenina/metabolismo

Palabras clave

MiR-708-5p; high phosphate; pit-1; vascular calcification

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: MicroARNs / Factor de Transcripción Pit-1 / Calcificación Vascular Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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