A novel fluorescent probe with large Stokes shift for the detection of viscosity changes and its imaging in living cells.
Luminescence
; 37(7): 1120-1125, 2022 Jul.
Article
en En
| MEDLINE
| ID: mdl-35470958
ABSTRACT
As an important cellular microenvironmental parameter, viscosity could reflect the status of living cells. Small molecular fluorescent probes are a vital tool to measure the change of viscosity in living cells. A novel fluorescence probe ZL-1 with a large Stokes shift (in methanol it reached to 153 nm and in glycerol it reached to 125 nm) and excellent sensitivity toward viscosity was developed. The sharp enhancement of the emission intensity for the probe ZL-1 from low viscous methanol to high viscous glycerol indicated that the probe ZL-1 could respond to the viscosity variations. Moreover, the probe ZL-1 has been successfully utilized to detect of the viscosity variations in living cells.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Metanol
/
Colorantes Fluorescentes
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Año:
2022
Tipo del documento:
Article