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Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization.
Zhang, Rutan; Polenakovik, Hari; Barreras Beltran, Ismael A; Waalkes, Adam; Salipante, Stephen J; Xu, Libin; Werth, Brian J.
  • Zhang R; Department of Medicinal Chemistry, University of Washington School of Pharmacy, Seattle, Washington, USA.
  • Polenakovik H; Veterans Affairs Medical Center, Dayton, Ohio, USA.
  • Barreras Beltran IA; Department of Medicine, Wright State University Boonshoft School of Medicine, Dayton, Ohio, USA.
  • Waalkes A; Department of Pharmacy, University of Washington School of Pharmacy, Seattle, Washington, USA.
  • Salipante SJ; Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
  • Xu L; Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
  • Werth BJ; Department of Medicinal Chemistry, University of Washington School of Pharmacy, Seattle, Washington, USA.
Clin Infect Dis ; 75(9): 1641-1644, 2022 10 29.
Article en En | MEDLINE | ID: mdl-35510938
ABSTRACT
A patient with end-stage renal disease received 2 doses of dalbavancin for methicillin-resistant Staphylococcus aureus (MRSA) arteriovenous fistula infection and presented 5 weeks later with infective endocarditis secondary to vancomycin, daptomycin, and dalbavancin nonsusceptible MRSA. Resistance was associated with walK and scrA mutations, reduced long-chain lipid content, and reduced membrane fluidity.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Daptomicina / Staphylococcus aureus Resistente a Meticilina Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Daptomicina / Staphylococcus aureus Resistente a Meticilina Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article