The risk factors of preterm birth: A multicentre case-control survey in China in 2018.
J Paediatr Child Health
; 58(8): 1396-1406, 2022 08.
Article
en En
| MEDLINE
| ID: mdl-35524688
ABSTRACT
OBJECTIVES:
To investigate the risk profile of preterm birth (PTB) in 2018 in China.METHOD:
A prospective multicentre case-control study was conducted in 15 hospitals located in seven provinces throughout three geographical areas (the Eastern, South-Central and North-Western regions) in China. A total of 3147 preterm (<37+0 weeks) and 3147 term (37+0 to 41+6 weeks) live-birth mothers were included. Designed questionnaires were used to investigate maternal and fetal information. We calculated multivariable logistic regression and population attributable risk (PAR).RESULTS:
Iatrogenic PTB accounted for 48.1% of preterm mothers. Multivariable analysis showed PTB was significantly associated with six categories of maternal and fetal factors, adverse life-style and psychological conditions (adjusted odds ratio (aOR) 2.063, 95% confidence interval (CI) 1.601-2.657) had the highest PAR% (60.1%). High school and below education level (PAR% = 25.8%), living in town or village (PAR% = 24.4%), low pregnant weight gain (PAR% = 16.8%), hypertensive disorders in pregnancy (aOR 5.010, 95% CI 4.039-6.216, PAR% = 15.3%), placental abnormality (aOR 4.242, 95% CI 3.454-5.211, PAR% = 14.1%) and multiple pregnancy (aOR 10.990, 95% CI 7.743-15.599, PAR% = 11.8%) were significantly associated with PTB with high PAR% value.CONCLUSION:
The main risk factors for PTB in China were placental abnormality, hypertensive disorders in pregnancy and multiple pregnancy. Adverse life-style and psychological conditions and socio-economic disadvantage had high public health significance.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Hipertensión Inducida en el Embarazo
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Nacimiento Prematuro
Tipo de estudio:
Clinical_trials
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Etiology_studies
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Observational_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Newborn
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Pregnancy
País como asunto:
Asia
Idioma:
En
Año:
2022
Tipo del documento:
Article