[Recent research on tofacitinib in the treatment of pediatric rheumatic diseases]. / ææ³æ¿å°¼å¨å¿ç«¥é£æ¹¿æ§ç¾ç
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Zhongguo Dang Dai Er Ke Za Zhi
; 24(4): 447-453, 2022 Apr 15.
Article
en Zh
| MEDLINE
| ID: mdl-35527423
ABSTRACT
Tofacitinib is a Janus kinase inhibitor and can block the Janus kinase-signal transducer and activator of transcription signal transduction pathway and reduce the production and release of a variety of cytokines. It has great potential in the treatment of various rheumatic diseases with a rapid onset of action and can reduce corticosteroid dependence and related adverse events. The therapeutic effect of tofacitinib in adult patients has been confirmed, and it has been increasingly used in pediatric patients in recent years. This article reviews the clinical application of tofacitinib in the treatment of pediatric autoimmune diseases.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Piperidinas
/
Enfermedades Reumáticas
Límite:
Adult
/
Child
/
Humans
Idioma:
Zh
Año:
2022
Tipo del documento:
Article