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Fighting the Huntington's Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies.
Riccardi, Claudia; D'Aria, Federica; Digilio, Filomena Anna; Carillo, Maria Rosaria; Amato, Jussara; Fasano, Dominga; De Rosa, Laura; Paladino, Simona; Melone, Mariarosa Anna Beatrice; Montesarchio, Daniela; Giancola, Concetta.
  • Riccardi C; Department of Chemical Sciences, University of Naples Federico II, 80126 Napoli, Italy.
  • D'Aria F; Department of Pharmacy, University of Naples Federico II, 80131 Napoli, Italy.
  • Digilio FA; Research Institute on Terrestrial Ecosystems (IRET), UOS Naples-CNR, 80131 Napoli, Italy.
  • Carillo MR; Research Institute on Terrestrial Ecosystems (IRET), UOS Naples-CNR, 80131 Napoli, Italy.
  • Amato J; Department of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.
  • Fasano D; Department of Pharmacy, University of Naples Federico II, 80131 Napoli, Italy.
  • De Rosa L; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Napoli, Italy.
  • Paladino S; Center for Rare Diseases and Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, 2nd Division of Neurology, University of Campania Luigi Vanvitelli, 80131 Napoli, Italy.
  • Melone MAB; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Napoli, Italy.
  • Montesarchio D; Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Napoli, Italy.
  • Giancola C; Center for Rare Diseases and Inter University Center for Research in Neurosciences, Department of Advanced Medical and Surgical Sciences, 2nd Division of Neurology, University of Campania Luigi Vanvitelli, 80131 Napoli, Italy.
Int J Mol Sci ; 23(9)2022 Apr 27.
Article en En | MEDLINE | ID: mdl-35563194
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article