The importance of timing in epilepsia partialis continua.
Neurologia (Engl Ed)
; 37(4): 263-270, 2022 May.
Article
en En
| MEDLINE
| ID: mdl-35595402
ABSTRACT
INTRODUCTION:
Timing is one of the most important modifiable prognostic factors in the management of status epilepticus. Epilepsia partialis continua (EPC) is a status epilepticus subtype of highly variable, occasionally prolonged, duration. The aim of this study was to analyse the relationship between EPC duration and outcomes.METHODS:
We performed an observational prospective study of all patients with EPC admitted to our tertiary hospital between 1 September 2017 and 1 September 2018.RESULTS:
The sample included 10 patients, of whom 9 were women; median age was 74 years. The most frequent aetiology was cerebrovascular disease (nâ¯=â¯6). EPC onset occurred outside the hospital in 5 patients, with a median time to hospital admission of 4â¯hours. The median time to treatment onset (TT) for all patients was 12.3â¯hours. The median time from treatment onset to EPC control (TC) was 30â¯hours; TC showed a strong positive correlation with TT (Spearman's rhoâ¯=â¯0.88). Six patients presented hyperglycaemia at onset; this was positively correlated with TC (rhoâ¯=â¯0.71). All 6 patients with hyperglycaemia presented a brain injury explaining the EPC episode.CONCLUSIONS:
Delays were observed in different phases of EPC management, which was related to longer duration of the episode. Glycaemia was also related to episode duration, probably acting as a triggering factor rather than as the aetiology.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Estado Epiléptico
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Epilepsia Parcial Continua
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Hiperglucemia
Tipo de estudio:
Etiology_studies
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Observational_studies
/
Prognostic_studies
Límite:
Aged
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Female
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Humans
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Male
Idioma:
En
Año:
2022
Tipo del documento:
Article