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TRF2 inhibition rather than telomerase disruption drives CD4T cell dysfunction during chronic viral infection.
Nguyen, Lam Ngoc Thao; Nguyen, Lam Nhat; Zhao, Juan; Schank, Madison; Dang, Xindi; Cao, Dechao; Khanal, Sushant; Wu, Xiao Y; Zhang, Yi; Zhang, Jinyu; Ning, Shunbin; Wang, Ling; El Gazzar, Mohamed; Moorman, Jonathan P; Yao, Zhi Q.
  • Nguyen LNT; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Nguyen LN; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Zhao J; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Schank M; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Dang X; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Cao D; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Khanal S; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Wu XY; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Zhang Y; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Zhang J; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Ning S; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Wang L; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • El Gazzar M; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Moorman JP; Department of Internal Medicine, Division of Infectious, Inflammatory and Immunologic Diseases, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
  • Yao ZQ; Center of Excellence in Inflammation, Infectious Disease and Immunity, Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, USA.
J Cell Sci ; 135(13)2022 07 01.
Article en En | MEDLINE | ID: mdl-35660868
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Infecciones por VIH / Telomerasa / Proteína 2 de Unión a Repeticiones Teloméricas Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Linfocitos T CD4-Positivos / Infecciones por VIH / Telomerasa / Proteína 2 de Unión a Repeticiones Teloméricas Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article