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RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.
Fang, Lishan; Ford-Roshon, Dane; Russo, Max; O'Brien, Casey; Xiong, Xiaozhe; Gurjao, Carino; Grandclaudon, Maximilien; Raghavan, Srivatsan; Corsello, Steven M; Carr, Steven A; Udeshi, Namrata D; Berstler, James; Sicinska, Ewa; Ng, Kimmie; Giannakis, Marios.
  • Fang L; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Ford-Roshon D; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Russo M; Medical Research Center, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
  • O'Brien C; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Xiong X; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Gurjao C; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Grandclaudon M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Raghavan S; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Corsello SM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Carr SA; Department of Urology, Boston Children's Hospital, Boston, MA, USA.
  • Udeshi ND; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Berstler J; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Sicinska E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ng K; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Giannakis M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Commun ; 13(1): 3181, 2022 06 08.
Article en En | MEDLINE | ID: mdl-35676246
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Fosfatidilinositol 3-Quinasas / Ubiquitina-Proteína Ligasas / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Fosfatidilinositol 3-Quinasas / Ubiquitina-Proteína Ligasas / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article