Animal Models of Cardiovascular Complications of Pregnancy.
Circ Res
; 130(12): 1763-1779, 2022 06 10.
Article
en En
| MEDLINE
| ID: mdl-35679359
ABSTRACT
Cardiovascular complications of pregnancy have risen substantially over the past decades, and now account for the majority of pregnancy-induced maternal deaths, as well as having substantial long-term consequences on maternal cardiovascular health. The causes and pathophysiology of these complications remain poorly understood, and therapeutic options are limited. Preclinical models represent a crucial tool for understanding human disease. We review here advances made in preclinical models of cardiovascular complications of pregnancy, including preeclampsia and peripartum cardiomyopathy, with a focus on pathological mechanisms elicited by the models and on relevance to human disease.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Preeclampsia
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Complicaciones Cardiovasculares del Embarazo
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Cardiomiopatías
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Animals
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Female
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Humans
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Pregnancy
Idioma:
En
Año:
2022
Tipo del documento:
Article