The relationship between sex, personality traits, and the hypothalamic-pituitary-adrenocortical axis.
Arch Womens Ment Health
; 25(4): 693-703, 2022 08.
Article
en En
| MEDLINE
| ID: mdl-35732898
ABSTRACT
The aim of our study was to examine whether there are sex-based differences in the relationship between personality traits and hypothalamic-pituitary-adrenal (HPA) axis measures. A total of 106 healthy volunteers (56.6% women; age 48.0 ± 15.8 years) were studied. The revised temperament and character inventory (TCI-R) and the Childhood Trauma Questionnaire (CTQ) were administered. HPA axis function was assessed using three dynamic measures:
the cortisol awakening response (CAR), the diurnal cortisol slope, and the cortisol suppression ratio with 0.25 mg of dexamethasone (DSTR). Female sex was associated with an increased CAR and a more flattened diurnal cortisol slope, although a negative significant interaction between harm avoidance and female sex was found. Regarding the DSTR, perseverance was associated with increased cortisol suppression after dexamethasone; sex did not affect this association. Our study suggests that the relationship between specific personality traits (harm avoidance) and HPA axis measures (CAR, diurnal slope) differs according to sex.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sistema Hipófiso-Suprarrenal
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Sistema Hipotálamo-Hipofisario
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2022
Tipo del documento:
Article