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Recent patents on water-soluble polysaccharides for advanced drug delivery, tissue engineering and regenerative medicine.
Adeyemi, Samson A; Choonara, Yahya E.
  • Adeyemi SA; Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy & Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa.
  • Choonara YE; Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy & Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown, 2193, South Africa.
Pharm Pat Anal ; 11(2): 75-88, 2022 Mar.
Article en En | MEDLINE | ID: mdl-35758101
Water-soluble polysaccharides have unique properties and have found wide application in the design of advanced drug-delivery systems and the biofabrication of tissue engineered scaffolds in regenerative medicine. This patent review provides a concise incursion into the mechanisms that define the key properties of water-soluble polysaccharides that have found embodiment within active patents recently granted (2020-2021). In addition, the relationship between their solubility and structural features such as molecular weight, ionic profile, degree of branching/crosslinking, side-chain flexibility and the presence/modification of functional groups that have been discusses. An assimilation of patents in which water-soluble polysaccharides are central to the design of therapeutic interventions applied to specialized treatments in oncology, infectious diseases and neuronal disorders is provided.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ingeniería de Tejidos / Medicina Regenerativa Idioma: En Año: 2022 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ingeniería de Tejidos / Medicina Regenerativa Idioma: En Año: 2022 Tipo del documento: Article