Association of pre-pregnancy body mass index and gestational weight gain with neonatal anogenital distance in a Chinese birth cohort.
Reprod Health
; 19(1): 152, 2022 Jun 29.
Article
en En
| MEDLINE
| ID: mdl-35768839
In China, the prevalence of underweight and overweight/obesity remained high among women. Appropriate pre-pregnancy body mass index (BMI) and gestation weight gain (GWG) were critical to reduce the risk of adverse birth outcomes. The anogenital distance (AGD) was measured as an indicator of neonatal reproductive function and was associated with adverse reproductive outcomes in adults. Thus, we investigated the associations of both sub-optimal pre-pregnancy BMI, as well as GWG, with AGD among newborns to draw a picture about their effect on offspring reproductive health.A total of 556 mother-newborns were included in the study from the Jiashan birth cohort in China. We extracted information about maternal lifestyles, social demographic characteristics, diet, and medical history from questionnaires conducted during 816 gestational weeks and medical records. AGD among newborns was measured within 3 days of delivery.We found that maternal excessive GWG was associated with shorter AGD in male newborns after adjusting for maternal pre-pregnancy BMI in multiple linear regression models. The study also suggested that maternal inadequate GWG was associated with a shorter AGD in male newborns, which needed to be corroborated in further studies with a larger sample size.In conclusion, health professionals shall implement sufficient intervention to prevent suboptimal GWG during prenatal checkups.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ganancia de Peso Gestacional
Tipo de estudio:
Prognostic_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Male
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Newborn
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Pregnancy
País como asunto:
Asia
Idioma:
En
Año:
2022
Tipo del documento:
Article