Pupil assessment with a new handheld pupillometer in healthy subjects.
Int Ophthalmol
; 43(1): 51-61, 2023 Jan.
Article
en En
| MEDLINE
| ID: mdl-35821362
ABSTRACT
OBJECTIVE:
To assess the pupil response with a new handheld pupillometer in healthy subjects.METHODS:
Sixty-four eyes of 32 healthy subjects (mean age 21.2 years) were tested. After dark adaptation for 10 min, pupil responses to 1 s red and blue light stimuli at 100 cd/m2 were measured in the order from right to left eyes with a 1 min interval. The initial pupil size (D1, mm), minimum pupil size (D2, mm), and constriction rate (CR, %) were obtained. Intra-examiner reproducibility was examined using the coefficient of variation (CV, %) and the Bland-Altman plot. Inter-examiner consistency was examined using the interclass correlation coefficient (ICC) and the agreements with a conventional device, by Pearson's correlation coefficient (r).RESULTS:
The CV of all parameters have high reproducibility in the red (11.0-20.7%) and blue (5.5-12.1%) light stimuli. Bland-Altman plot analysis showed no bias with both light stimuli. "Almost perfect" and "substantial" correlations between the examiners were obtained in the red (ICC = 0.78-0.94) and blue (ICC = 0.71-0.89) light stimuli. "Excellent" and "good" correlations between the devices were obtained, except for the CR parameter in the red (D1 r = 0.90; p < 0.001, D2 0.72; p < 0.001, and CR 0.08; p = 0.631, respectively) and blue (D1 r = 0.87; p < 0.001, D2 0.70; p < 0.001, and CR 0.19; p = 0.274, respectively) light stimuli.CONCLUSION:
The novel pupillometer is useful for assessing pupil response. However, because of their different constructions, the CR values cannot be compared directly between the devices.Palabras clave
Texto completo:
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Banco de datos:
MEDLINE
Asunto principal:
Pupila
/
Técnicas de Diagnóstico Oftalmológico
Límite:
Adult
/
Humans
Idioma:
En
Año:
2023
Tipo del documento:
Article