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Reduced dynamic loads due to hip dislocation induce acetabular cartilage degeneration by IL-6 and MMP3 via the STAT3/periostin/NF-κB axis.
Nakamura, Yutaka; Saitou, Mitsuru; Komura, Shingo; Matsumoto, Kazu; Ogawa, Hiroyasu; Miyagawa, Takaki; Saitou, Takashi; Imamura, Takeshi; Imai, Yuuki; Takayanagi, Hiroshi; Akiyama, Haruhiko.
  • Nakamura Y; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Saitou M; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Komura S; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Matsumoto K; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Ogawa H; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Miyagawa T; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.
  • Saitou T; Department of Molecular Medicine for Pathogenesis, Graduate School of Medicine, Ehime University, Toon, Ehime, 791-0295, Japan.
  • Imamura T; Department of Molecular Medicine for Pathogenesis, Graduate School of Medicine, Ehime University, Toon, Ehime, 791-0295, Japan.
  • Imai Y; Division of Integrative Pathophysiology, Proteo-Science Center, Ehime University, Toon, Ehime, 791-0295, Japan.
  • Takayanagi H; Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Akiyama H; Department of Orthopaedic Surgery, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan. hakiyama@gifu-u.ac.jp.
Sci Rep ; 12(1): 12207, 2022 07 16.
Article en En | MEDLINE | ID: mdl-35842459
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades de los Cartílagos / Luxación de la Cadera Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades de los Cartílagos / Luxación de la Cadera Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article