Florid cemento-osseous dysplasia-related osteonecrosis: A series of cases.
Ann Diagn Pathol
; 60: 152009, 2022 Oct.
Article
en En
| MEDLINE
| ID: mdl-35868115
ABSTRACT
OBJECTIVE:
The aim of this study was to assess the clinicopathological features of florid cemento-osseous dysplasia (FCOD)-related osteonecrosis highlighting their histopathological aspects and bone structure.METHODS:
Twenty-two FCOD-related osteonecrosis cases were evaluated retrospectively. Osteonecrosis, osteomyelitis, bacterial colonization, bone resorption, reactive bone, osteon-like structure, lamellar bone, and basophilic lines were analyzed. Specific staining and fluorescence and polarized light microscopy analyses were also performed.RESULTS:
The mandible was more affected by FCOD-related osteonecrosis. There was a predominance of African-Brazilian women in the fifth and seventh decades of life. Osteomyelitis was present in 82 % of cases whereas bone resorption and bacterial colonization were present in 100 % of FCOD-related osteonecrosis cases. Thick basophilic lines were seen in all cases (100 %). Actinomycosis and osteoclasts were not often.CONCLUSIONS:
This study showed female adult preference, mandibular location, and some findings such as osteomyelitis, bone resorption, and bacterial colonization were histopathological features more frequent in FCOD-related osteonecrosis. In the absence of a close clinical and radiographic correlation, the morphology of the necrotized bone similar to cementum could help to recognize FCOD.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Osteomielitis
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Osteonecrosis
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Resorción Ósea
Tipo de estudio:
Observational_studies
Límite:
Adult
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Female
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Humans
Idioma:
En
Año:
2022
Tipo del documento:
Article