Your browser doesn't support javascript.
loading
Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis.
Najafi, Sajad; Khatami, Seyyed Hossein; Khorsand, Marjan; Jamali, Zeinab; Shabaninejad, Zahra; Moazamfard, Mostafa; Majidpoor, Jamal; Aghaei Zarch, Seyed Mohsen; Movahedpour, Ahmad.
  • Najafi S; Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: sajadnajafi1990@yahoo.com.
  • Khatami SH; Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Khorsand M; Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Jamali Z; Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Shabaninejad Z; Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
  • Moazamfard M; Behbahan Faculty of Medical Sciences, Behbahan, Iran.
  • Majidpoor J; Department of Anatomy, Faculty of Medicine, Infectious Disease Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
  • Aghaei Zarch SM; Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Movahedpour A; Behbahan Faculty of Medical Sciences, Behbahan, Iran. Electronic address: ahmad.movahed14@gmail.com.
Exp Cell Res ; 418(2): 113294, 2022 09 15.
Article en En | MEDLINE | ID: mdl-35870535
ABSTRACT
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a broad range of biological processes, including the pathogenesis of many complex human diseases, including cancer. The detailed regulation mechanisms of many lncRNAs in cancer initiation and progression have yet to be discovered, even though a few of lncRNAs' functions in cancer have been characterized. In the present study, we summarize recent advances in the mechanisms and functions of lncRNAs in cancer. We focused on the roles of newly-identified lncRNAs as oncogenes and tumor suppressors, as well as the potential pathways these molecules could play. The paper also discusses their potential uses as biomarkers for the diagnosis and prognosis of cancer.
Asunto(s)
Palabras clave
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Largo no Codificante / Neoplasias Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Largo no Codificante / Neoplasias Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article