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High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis.
Diebold, Martin; Galli, Edoardo; Kopf, Andreas; Sanderson, Nicholas S R; Callegari, Ilaria; Benkert, Pascal; Gonzalo Núñez, Nicolás; Ingelfinger, Florian; Herms, Stefan; Cichon, Sven; Kappos, Ludwig; Kuhle, Jens; Becher, Burkhard; Claassen, Manfred; Derfuss, Tobias.
  • Diebold M; Multiple Sclerosis Center, Neurologic Clinic and Policlinic, Department of Biomedicine and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel 4031, Switzerland.
  • Galli E; Institute of Neuropathology, Neurozentrum, University Hospital Freiburg, University of Freiburg, Freiburg 79106, Germany.
  • Kopf A; Multiple Sclerosis Center, Neurologic Clinic and Policlinic, Department of Biomedicine and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel 4031, Switzerland.
  • Sanderson NSR; Institute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
  • Callegari I; Institute of Molecular Systems Biology, ETH Zurich, Zurich 8093, Switzerland.
  • Benkert P; Personalized Health Informatics, Swiss Institute of Bioinformatics, Zurich 8093, Switzerland.
  • Gonzalo Núñez N; PhD Program Systems Biology, Life Science Graduate School Zurich, Zurich 8057, Switzerland.
  • Ingelfinger F; Multiple Sclerosis Center, Neurologic Clinic and Policlinic, Department of Biomedicine and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel 4031, Switzerland.
  • Herms S; Multiple Sclerosis Center, Neurologic Clinic and Policlinic, Department of Biomedicine and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel 4031, Switzerland.
  • Cichon S; Multiple Sclerosis Center, Neurologic Clinic and Policlinic, Department of Biomedicine and Research Center for Clinical Neuroimmunology and Neuroscience Basel (RC2NB), University Hospital Basel, University of Basel, Basel 4031, Switzerland.
  • Kappos L; Department of Clinical Research, University Hospital Basel, University of Basel, Basel 4031, Switzerland.
  • Kuhle J; Institute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
  • Becher B; Institute of Experimental Immunology, University of Zurich, Zurich 8057, Switzerland.
  • Claassen M; Department of Neurology, University Hospital Zurich, Zurich 8091, Switzerland.
  • Derfuss T; Department of Genetics and Biomedicine, University Hospital Basel, University of Basel, Basel 4031, Switzerland.
Proc Natl Acad Sci U S A ; 119(31): e2205042119, 2022 08 02.
Article en En | MEDLINE | ID: mdl-35881799

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citocinas / Linfocitos T Colaboradores-Inductores / Biomarcadores Farmacológicos / Dimetilfumarato / Inmunosupresores / Esclerosis Múltiple Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Citocinas / Linfocitos T Colaboradores-Inductores / Biomarcadores Farmacológicos / Dimetilfumarato / Inmunosupresores / Esclerosis Múltiple Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article