Low-Dose-Rate Radiation-Induced Secretion of TGF-ß3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding.

Hanson, Ingunn; Pitman, Kathinka E; Altanerova, Ursula; Altaner, Cestmír; Malinen, Eirik; Edin, Nina F J

Hanson, Ingunn; Pitman, Kathinka E; Altanerova, Ursula; Altaner, Cestmír; Malinen, Eirik; Edin, Nina F J.

Hanson I; Department of Physics, University of Oslo, 0371 Oslo, Norway.
Pitman KE; Department of Physics, University of Oslo, 0371 Oslo, Norway.
Altanerova U; Department of Stem Cell Preparation, St. Elisabeth Cancer Institute, 84505 Bratislava, Slovakia.
Altaner C; Department of Stem Cell Preparation, St. Elisabeth Cancer Institute, 84505 Bratislava, Slovakia.
Malinen E; Cancer Research Institute, Slovak Academy of Sciences, Bratislava, 94505 Bratislava, Slovakia.
Edin NFJ; Department of Physics, University of Oslo, 0371 Oslo, Norway.

Int J Mol Sci ; 23(15)2022 Jul 24.

Article en En | MEDLINE | ID: mdl-35897723

Asunto(s)

Vesículas Extracelulares; Factor de Crecimiento Transformador beta3; Línea Celular; Vesículas Extracelulares/metabolismo; Dosis de Radiación; Tolerancia a Radiación/fisiología; Factor de Crecimiento Transformador beta/metabolismo

Palabras clave

ADAM; ALK1; ALK5; MMP; TGF-ß3; adaptive response; bystander effects; hyper-radiosensitive response; low dose rate; low-dose radiation

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta3 / Vesículas Extracelulares Idioma: En Año: 2022 Tipo del documento: Article

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