Regulation of TIA-1 Condensates: Zn<sup>2+</sup> and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation.

Regulation of TIA-1 Condensates: Zn²⁺ and RGG Motifs Promote Nucleic Acid Driven LLPS and Inhibit Irreversible Aggregation.

West, Danella L; Loughlin, Fionna E; Rivero-Rodríguez, Francisco; Vankadari, Naveen; Velázquez-Cruz, Alejandro; Corrales-Guerrero, Laura; Díaz-Moreno, Irene; Wilce, Jacqueline A.

West DL; Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
Loughlin FE; Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
Rivero-Rodríguez F; Institute for Chemical Research, University of Seville-CSIC, Seville, Spain.
Vankadari N; Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.
Velázquez-Cruz A; Institute for Chemical Research, University of Seville-CSIC, Seville, Spain.
Corrales-Guerrero L; Institute for Chemical Research, University of Seville-CSIC, Seville, Spain.
Díaz-Moreno I; Institute for Chemical Research, University of Seville-CSIC, Seville, Spain.
Wilce JA; Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia.

Front Mol Biosci ; 9: 960806, 2022.

Article en En | MEDLINE | ID: mdl-35911965