PfSPZ-CVac malaria vaccine demonstrates safety among malaria-experienced adults: A randomized, controlled phase 1 trial.
EClinicalMedicine
; 52: 101579, 2022 Oct.
Article
en En
| MEDLINE
| ID: mdl-35928033
ALT, alanine aminotransferase; CHMI, Controlled Human Malaria Infection; CQ, chloroquine; CSP, circumsporozoite protein; DOT, directly observed therapy; DVI, direct venous inoculation; ELISA, enzyme linked immunosorbent assay; HR, hazard ratio; Malaria vaccine; PCR, polymerase chain reaction; Pf, Plasmodium falciparum; PfSPZ Vaccine; PfSPZ-CVac; PfSPZ-CVac, Plasmodium falciparum Sporozoite Chemoprophylaxis Vaccine; Plasmodium falciparum; SMC, safety monitoring committee; SPZ, sporozoite; Sporozoite; TBS, thick blood smear; VE, vaccine efficacy
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MEDLINE
Tipo de estudio:
Clinical_trials
/
Guideline
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Prognostic_studies
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En
Año:
2022
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Article