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LLPS of FXR1 drives spermiogenesis by activating translation of stored mRNAs.
Kang, Jun-Yan; Wen, Ze; Pan, Duo; Zhang, Yuhan; Li, Qing; Zhong, Ai; Yu, Xinghai; Wu, Yi-Chen; Chen, Yu; Zhang, Xiangzheng; Kou, Peng-Cheng; Geng, Junlan; Wang, Ying-Yi; Hua, Min-Min; Zong, Ruiting; Li, Biao; Shi, Hui-Juan; Li, Dangsheng; Fu, Xiang-Dong; Li, Jinsong; Nelson, David L; Guo, Xuejiang; Zhou, Yu; Gou, Lan-Tao; Huang, Ying; Liu, Mo-Fang.
  • Kang JY; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Wen Z; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Pan D; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Zhang Y; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai Research Center of Biliary Tract Disease, Department of General Surgery, Xinhua Hospital, affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Li Q; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Zhong A; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Yu X; State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, China.
  • Wu YC; Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China.
  • Chen Y; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Zhang X; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
  • Kou PC; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
  • Geng J; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Wang YY; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Hua MM; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Zong R; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Li B; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, Shanghai, China.
  • Shi HJ; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Li D; Department of Nuclear Medicine, Rui Jin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
  • Fu XD; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Pharmacy School, Fudan University, Shanghai, China.
  • Li J; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Nelson DL; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA.
  • Guo X; State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Science
  • Zhou Y; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.
  • Gou LT; School of Life Science and Technology, Shanghai Tech University, Shanghai, China.
  • Huang Y; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Liu MF; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
Science ; 377(6607): eabj6647, 2022 08 12.
Article en En | MEDLINE | ID: mdl-35951695

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Espermátides / Espermatogénesis / Biosíntesis de Proteínas / Proteínas de Unión al ARN / Regulación del Desarrollo de la Expresión Génica / ARN Mensajero Almacenado Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Espermátides / Espermatogénesis / Biosíntesis de Proteínas / Proteínas de Unión al ARN / Regulación del Desarrollo de la Expresión Génica / ARN Mensajero Almacenado Límite: Animals Idioma: En Año: 2022 Tipo del documento: Article