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Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties.
Liu, Rui; Marshall, Kate; Ma, Rui; Lien Thi Pham, Kim; Shetye, Gauri; Liu, Zhihao; Cho, Sanghyun; Jeong, Hyunyoung; Franzblau, Scott G; Moraski, Garrett C; Miller, Marvin J.
  • Liu R; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
  • Marshall K; Department of Chemistry and Biochemistry, Montana State University, 103 Chemistry and Biochemistry, Bozeman, Montana 59717, USA.
  • Ma R; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Lien Thi Pham K; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Shetye G; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Liu Z; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Cho S; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Jeong H; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA.
  • Moraski GC; Department of Chemistry and Biochemistry, Montana State University, 103 Chemistry and Biochemistry, Bozeman, Montana 59717, USA. Electronic address: garrett.moraski@montana.edu.
  • Miller MJ; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address: mmiller1@nd.edu.
Bioorg Chem ; 128: 106074, 2022 11.
Article en En | MEDLINE | ID: mdl-35987188
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis / Mycobacterium tuberculosis Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article