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Discovery of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one and 3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one derivatives as novel ENPP1 inhibitors.
Jung, Jae Eun; Jang, Yunseong; Jeong, Hee Jin; Kim, Sung Joon; Park, Kichul; Oh, Do Hee; Yu, Ahran; Park, Chan Sun; Han, Seo-Jung.
  • Jung JE; Chemical & Biological Integrative Research Center, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
  • Jang Y; Chemical & Biological Integrative Research Center, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
  • Jeong HJ; Chemical & Biological Integrative Research Center, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
  • Kim SJ; Txinno Bioscience INC, 338 Gwanggyojungang-ro, Suji-gu, Yongin-si, Gyeonggi-do 16942, Republic of Korea.
  • Park K; OZIWORX. R&D Laboratory, 130-2, Donghwagongdan-ro, Wonju-si, Gangwon-do 26365, Republic of Korea.
  • Oh DH; Chemical & Biological Integrative Research Center, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
  • Yu A; Txinno Bioscience INC, 338 Gwanggyojungang-ro, Suji-gu, Yongin-si, Gyeonggi-do 16942, Republic of Korea.
  • Park CS; Txinno Bioscience INC, 338 Gwanggyojungang-ro, Suji-gu, Yongin-si, Gyeonggi-do 16942, Republic of Korea.
  • Han SJ; Chemical & Biological Integrative Research Center, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, University of Science and Technology, Seoul 02792, Republic of Korea.
Bioorg Med Chem Lett ; 75: 128947, 2022 11 01.
Article en En | MEDLINE | ID: mdl-35995398
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirofosfatasas / Hidrolasas Diéster Fosfóricas Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirofosfatasas / Hidrolasas Diéster Fosfóricas Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article