Elucidation of Key Interactions between VirF and the <i>virB</i> Promoter in Shigella flexneri Using E. coli MarA- and GadX-Based Homology Models and <i>In Vitro</i> Analysis of the DNA-Binding Domains of VirF and MarA.

Ragazzone, Nicholas J; Dow, Garrett T; Garcia, George A

Elucidation of Key Interactions between VirF and the virB Promoter in Shigella flexneri Using E. coli MarA- and GadX-Based Homology Models and In Vitro Analysis of the DNA-Binding Domains of VirF and MarA.

Ragazzone, Nicholas J; Dow, Garrett T; Garcia, George A.

Ragazzone NJ; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Dow GT; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Garcia GA; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA.

J Bacteriol ; 204(9): e0014322, 2022 Sep 20.

Article en En | MEDLINE | ID: mdl-36040161

Asunto(s)

Agua Potable; Disentería Bacilar; Alanina/genética; Antibacterianos/metabolismo; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Niño; Preescolar; ADN/metabolismo; Proteínas de Unión al ADN/genética; Proteínas de Unión al ADN/metabolismo; Agua Potable/metabolismo; Escherichia coli/metabolismo; Proteínas de Escherichia coli; Regulación Bacteriana de la Expresión Génica; Humanos; Factores Reguladores del Interferón/genética; Factores Reguladores del Interferón/metabolismo; Shigella flexneri/genética; Shigella flexneri/metabolismo; Transcripción Genética; Proteínas Virales; Factores de Virulencia/genética; Factores de Virulencia/metabolismo

Palabras clave

Shigella; virulence factors

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Agua Potable / Disentería Bacilar Tipo de estudio: Prognostic_studies Límite: Child / Child, preschool / Humans Idioma: En Año: 2022 Tipo del documento: Article

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