Physiologically Based Pharmacokinetic Modeling To Predict Drug-Biologic Interactions with Cytokine Modulators: Are These Relevant and Is Interleukin-6 Enough?

Chen, Kuan-Fu; Jones, Hannah M; Gill, Katherine L

Chen, Kuan-Fu; Jones, Hannah M; Gill, Katherine L.

Chen KF; Certara UK Limited (Simcyp Division), Sheffield, United Kingdom.
Jones HM; Certara UK Limited (Simcyp Division), Sheffield, United Kingdom.
Gill KL; Certara UK Limited (Simcyp Division), Sheffield, United Kingdom kate.gill@certara.com.

Drug Metab Dispos ; 50(10): 1322-1331, 2022 10.

Article en En | MEDLINE | ID: mdl-36100353

Asunto(s)

Productos Biológicos; Interleucina-6; Sistema Enzimático del Citocromo P-450/metabolismo; Citocinas; Interacciones Farmacológicas; Interleucina-10; Interleucina-17; Interleucina-2; Interleucina-6/metabolismo; Interleucina-8; Preparaciones Farmacéuticas/metabolismo; Factor de Necrosis Tumoral alfa; Factor A de Crecimiento Endotelial Vascular

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Productos Biológicos / Interleucina-6 Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Año: 2022 Tipo del documento: Article

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